Investigator I

The Opportunity:

As the Investigator I, LNP Chemistry and Formulation, you will work in the RNA Vaccine Process & Chemistry group and play the critical role on improvement of mRNA vaccines. You will design and execute experiments to improve the performance of the lipid nanoparticle (LNPs) by optimizing lipid chemistry and LNP formulation process and apply the improvement on the mRNA vaccine application.

The Role:

• Innovative LNP discovery and optimization to improve mRNA lipid nanoparticle vaccine platform.

• Design and develop novel lipids of delivery vehicles for nuclei acid-based payloads.

• Provide expertise to improve the scientific understanding of LNP chemistry and formulation process of mRNA vaccine.

• Performance of mRNA lipid nanoparticle formulations to support vaccine projects and preclinical development in animal models.

• Collaborate with internal and external partners in developing next- generation delivery systems for mRNA vaccines and beyond.

• Effectively communicate ideas, scientific findings, progress updates and prepare data summary presentation, compile data, and author technical reports.

• Support to maintain functional laboratory equipment, manage laboratory database and follow HSE regulation.

Your skills and Experience:

• PhD in Chemistry, Chemical Engineering, Pharmaceutical Science, or related fields with 0+ years of postdoc experience

• Academic or biotech experience with lipid chemistry or LNP is required.

• Experience with LNP characterization techniques such as DLS-Zeta measurement and electron microscopy is required.

• Experience with common laboratory and analytical techniques, such as UV/vis spectroscopy, HPLC, fluorescence assays are preferred.

• The ability to produce accurate and reproducible results while working on multiple tasks is required.

• The ability to work in teams with written/oral communication skills are required.

Our Benefits

CSL Seqirus employees that work at least 30 hours per week are eligible for benefits effective day 1. We are committed to the wellbeing of our employees and their loved ones. CSL Seqirus offers resources and benefits, from health care to financial protection, so you can focus on doing work that matters. Our benefits are designed to support the needs of our employees at every stage of their life. Whether you are considering starting a family, need help paying for emergency back up care or summer camp, looking for mental health resources, planning for your financial future, or supporting your favorite charity with a matching contribution, CSL Seqirus has many benefits to help achieve your goals.

Please take the time to review our benefits site to see what’s available to you as a CSL Seqirus employee.

About CSL Seqirus CSL Seqirus is part of CSL Limited (ASX: CSL). As one of the largest influenza vaccine providers in the world, CSL Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. Learn more about CSL Seqirus.

We want CSL Seqirus to reflect the world around us

As a global organization with employees in 35+ countries, CSL embraces diversity and inclusion. Learn more about Diversity & Inclusion at CSL Seqirus.

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Location: Waltham, MA, US

Posted Date: 10/31/2024